Mock 11 Gangrene
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STEM: 80 y old man with black discoloration of great toe.
Gangrene
Necrosis & Apoptosis
Necrosis
Enlarged cells
Frequent adjacent inflammation
Pathological mainly
Disrupted plasma membrane
Apoptosis
Cell shrink, no adjacent inflammation, physiological, Intact plasma membraneWet and Dry
Wet; more common in bowel, more with venous obstruction, putrefaction, numerous bacteria
Dry; more in limbs, arterial occlusion, limited putrefaction, no bacteria as cant survivepost hypoxia vasodilation
Foam cells
Smoking, Family hx, Hyperlipidema
Medium and large
collagen & fibrosis
Asbestos exposure cancer risk
sputum for cytology
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A admin moved this topic from Pathology
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