1. Enable Legacy Extension Support
    Open Chrome and go to:
    chrome://flags
    In the search bar at the top of that page, type: Allow legacy extension manifest versions
    When it appears, set it to Enabled.
    Click the Relaunch button in the bottom right to restart Chrome.

2. Download uBlock Origin (Safe & Official Source)
    Go to the GitHub release page: 👉 https://github.com/gorhill/uBlock/releases
    Find the latest version at the top.
    Under Assets, download:
    uBlock0.chromium.zip

3. Extract the ZIP File

    On Windows: Right-click the file and choose "Extract All"
    On macOS: Double-click the zip to extract it

This will create a folder with all the uBlock extension files inside.

4. Load the Extension Manually in Chrome
    Open Chrome and go to:
    chrome://extensions
    Toggle Developer Mode ON (top-right corner).
    Click the "Load unpacked" button (top-left).
    In the file picker window, select the folder you just extracted from the zip file (not the zip itself).

I had to delete the old ublock origin extension, and load the downloaded version, the flag didn't work in place.

Stolen from reddit: https://redlib.catsarch.com/r/Adblock/comments/1luqxs1/whats_currently_the_best_way_to_force_reenable/n2wq967

But it does work for me.

I reckon you know about this already, but I've seen a lot of posts on the fediverse about using uBlock Origin with Noscript because uMatrix stopped being supported. It seems that some haven't realized that uMatrix's functionality is in uBlock Origin!

Blocking mode: hard mode

uBlock Origin - An efficient blocker for Chromium and Firefox. Fast and lean. - Blocking mode: hard mode · gorhill/uBlock Wiki

GitHub (github.com)

So I thought I'd put it here just in case.