PRESENTATION John, a 56-year-old occupation, previously fit/smoker/social drinker who is on his 5th POD following ... [e.g. right hemicolectomy], has showed signs of anhedonia, depression and fatigue. He has also showed some signs of positive core biological symptoms. Considering all of this, my provisional diagnosis is reactive (postoperative depression), I will also consider major depressive disorder, bipolar disorder. What will be your management? For mild condition Regular exercise Advice on sleep hygiene (regular sleep times, appropriate environment) = Psychosocial therapy -CBT Moderate to severe Regular exercise, advice on sleep hygiene CBT Medication -SSRIs High-intensity psychosocial intervention (CBT or interpersonal therapy) Immediate and considerable high risk to themselves or others: Admit to psychiatric ward (use Mental Health Act if necessary)